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A pragmatic alternative is to prepare smaller vials from your reconstituted stock and freeze them as single-use aliquots at 20C, minimizing repeated freeze-thaw exposure to your main vial

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Thus K63-linked polyubiquitination seems to play a new role as a redox-regulator of protein translation by ribosomes, while K48-linked polyubiquitination regulates protein degradation by proteasomes

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