The interaction of carotenoids with Nrf2 enhances its translocation into the nucleus, which in turn activates glutathione S-transferases, an important family of detoxification enzymes that suppresses the level of oxidative stress
Savage et al., 1998), even as newer drugs with fewer, if any, metabolic issues (e.g., ACE inhibitors, calcium channel blockers and -blockers) began to replace it (Officers et al., 2002
ERK1/2 activation triggers transcription factors c-Fos and c-Jun that coordinate cellular repair responses
Key Takeaway: Glutathione is a vital tripeptide that supports cellular protection, but its effectiveness depends entirely on how well your body can absorb it through the digestive tract
Acknowledgements Thanks to Figdraw for providing painting assistance