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Copper is an essential trace mineral involved in more than a dozen enzymatic reactions in the human body including those governing connective tissue formation, antioxidant defense, cellular respiration, and blood clotting

762 , 763 In studies of dementia caregivers of relatives living in nursing homes or similar residential settings, caregivers indicated a number of challenges during the COVID19 pandemic, including severely limited contact with relatives due to visitation restrictions, a lack of transparent information and communication from care residences, fears of relatives dying alone and concerns about overburdened staff at care residences

Inspired by this idea long acting dual agonists were developed to treat type 2 diabetes and several obesity related health issues

These changes represent the body's adaptive response to perceived metabolic stress

Most research is on rats and mice