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Using an alternative strategy, targeting tumor endothelium and TEM8-positive malignant cells by employing TEM8-specific CAR T cells was effective in treating triple negative breast cancer (TNBC) patient derived xenograft (PDX) models and metastatic TNBC cell-line xenografts [324]

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Power spectral analysis of EEG frequency bands allows researchers to objectively characterize delta, theta, and spindle activity in treated versus control animals

Targeted pharmacologic therapies should be administered in appropriate patients (eg, carbidopa- levodopa in patients with Parkinson disease), but in these patients dysphagia is frequently progressive