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Glutathione is a powerful antioxidant that plays a crucial role in the detoxification of harmful substances in the liver

Since the hallmark of SCD is chronic hemolysis with excess hemin producing significant levels of oxidative stress, we speculate that hemin may modulate TSS pathway function

Introduction Glutathione is often hailed as a powerhouse antioxidant, playing a vital role in detoxification, immune function, and cellular health

Kondo, K., Sano, R., Goto, K., Hiramoto, K

Additionally, ferroptosis also participates in the genesis and progression of ALD through interactions with other organs within the hepatic microenvironment, primarily involving the liver-gut and the liver-adipose tissue axis [191]