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The tobacco leaf contains many alkaloid chemicals (nicotine is the most copious) which often possess a natural pharmacologic defense against many insects

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[15] Cruz-Jimenez, L., Barrientos-Gutirrez, I., Zavala-Arciniega, L., Arillo-Santilln, E., Gallegos-Carrillo, K., Rodrguez-Bolaos, R., Gravely, S., & Thrasher, J

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