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With tobacco from the New World becoming more and more popular in Europe, rolling papers became a sought-after commodity, particularly in Spain and France, where artisans began refining production techniques, with rolling papers often used as a marker of sophistication and social status

Adolescents sometimes claim they "just got intrigued" or even thought smoking was "great"

Analyses of variance were performed on the plasma nicotine AUC 030 , AUC 3090 , Cmax 030 , and C 90 parameters, and a Wilcoxon Signed Rank Test was used for the t max030 parameter to assess differences between the e-cigarettes and the tobacco cigarette

Nat Rev Cardiol 18(8):547564 Wang JB, Olgin JE, Nah G, Vittinghoff E, Cataldo JK, Pletcher MJ et al (2018) Cigarette and e-cigarette dual use and risk of cardiopulmonary symptoms in the Health eHeart Study

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