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[8] Compared with saline, delayed T4 did not shrink the lesion volume a telling detail, because it means the benefit was not simply less initial damage yet it significantly reduced hippocampal cell loss, enhanced angiogenesis and neurogenesis in the injured cortex and hippocampus, increased oligodendrogenesis, and improved sensorimotor recovery and spatial learning

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It is four times more effective than GSH monoester [61]

Reported side effects are generally mild the most common is injection site irritation, and some patients report transient nausea with oral dosing

Consistent results were observed in a subanalysis of OS by high-dose steroid use in the durvalumab arm among participants who experienced an imAE, and interpretation of these results is again limited by the small number of participants within each subgroup