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Despite the small sample size used in the study, a certain level of significance for future research of cabozantinib can be still be derived from the findings

Pericytes, endfeet astrocytes and neurons are also involved in the BBB structure [6]

Cells were incubated for 18 h at 37 C

In particular, one of oridonin derivate (HAO472) is currently in phase I clinical trials in China for the treatment of a type of leukemia (Ding et al., 2016)