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Description

Endonuclease G cleavage of DNA in the nucleus results in DNA fragmentation indistinguishable from that seen during apoptosis32, and translocation of AIF to the nucleus results in chromatin condensation and DNA fragmentation80

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Its crucial to adhere to recommended cycle lengths (e.g., 30-60 days on, followed by an equal period off) to prevent this and maintain efficacy

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At week 20, bodyweight reductions were observed to be greater with cagrilintide 1.2 and 2.4 mg than with placebo (15.7% for cagrilintide 1.2 mg and 17.1% for cagrilintide 2.4 mg vs

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