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Broccoli: a unique vegetable that protects mammalian hearts through the redox cycling of the thioredoxin superfamily

Key Compounds for Dark Roast Melanoidins Chlorogenic Acid Lactones B-carboline Trigonelline, Niacin and N-methylpyridinium Below is a chart that summarizes key points, which are explained in more detail

Ann Neurol 2014;75:597601

Animal studies have shown that consumption of VD and LC is more effective in raising blood levels of 25(OH)VD (treating vitamin D deficiency) and lowering IR and inflammation compared to intake of vitamin D alone [82,153]

Further research in this area is of merit, to determine the impact and requirements for B vitamins and other nutrients that support methylation in individuals with this specific genetic polymorphism (Cirilo et al., 2021)