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Hormone disruption: It doesn't affect testosterone, estrogen, thyroid, or other hormones

While the trial was marked as completed, results were never published, and the manuscript submission was cancelled in 2016

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It provides enough semaglutide to last through the initial titration phases, reduces the per-milligram cost compared to smaller vials, and does not require the commitment of a 15 mg vial that might expire before you use it all

Some men find that significant weight loss normalizes previously low testosterone without requiring hormone replacement