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Frequently linked to hormones, heat, and light exposure, and known for fading and returning in cycles

Given their non-invasive nature, accessibility, and cost-effectiveness of sublingual formulations, they may represent a promising approach for long-term B12 management, particularly in patients with impaired absorption or in resource-limited settings

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The reduced Trx or GSH then distribute this NADPH-derived reducing power by their transmission of these electrons to other molecules, mainly via dithiol-disulfide exchange reactions