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154 Protein denaturation is a biochemical process that disrupts the hydrogen, hydrophobic, and disulfide bonds, which leads to alteration in the structure of the protein

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Aflatoxins are major concern with to public health and the most important toxicological interest in aflatoxins has concentrated on aflatoxin B1, largely due to its acute toxicity and carcinogenicity in humans and animals

We further interpret this statutory language to mean that CMS has discretion to approve or deny a request for an expansion exception even if the requesting hospital meets the criteria for an applicable hospital or high Medicaid facility