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The Connectivity Map approach compares the gene-expression signature a compound induces in cultured cells against a reference database of signatures, inferring which pathological patterns the compound might counteract

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GHK-Cu increases the expression of basic fibroblast growth factor and vascular endothelial growth factor, both of which aid blood vessel formation [45]

doi:10.1038/s41598-018-26567-2

Concomitant intramuscular human chorionic gonadotropin preserves spermatogenesis in men undergoing testosterone replacement therapy