They have roles in the development of certain human diseases whilst also performing physiological functions
Cleanup Let me expand on our water analogy, because it's crucial to understanding the right approach: Imagine your body is a kitchen with a sink
There is no ramp-up phase and no dose escalation
More Crohns and Colitis Stories Kristen F., Crohns Disease (IBD) Symptoms: Fatigue, abdominal cramps, blood in stool, loss of appetite, frequent and painful bathroom visits, perianal disease (open wound), mouth sores, joint pain Treatments: Multiple medications, surgeries (temporary ostomy, total colectomy and permanent ostomy, Barbie butt surgery or proctectomy) Jess G., Crohns Disease (IBD) Symptoms: No appetite even when offered a favorite dessert, weight loss Treatments: Steroids, blood transfusions, biologics, surgeries (colectomy, small bowel resection, colostomy) Ariel D., Ulcerative Colitis (IBD) Symptoms: Overactive bowel, heavy cramps in stomach area, abdominal pain Treatment: Surgery (ileostomy) Alli R., Ulcerative Colitis Symptoms: Blood in stool, unexplained weight loss, stomach pain, constant defecation Treatment: Surgery (ileostomy) Sarah A., Ulcerative Colitis Symptoms: Bowel irregularity, severe stomachaches, blood in stool Treatments: Surgery (ostomy surgery), steroids, anti-inflammatory medication (mesalamine), biologic therapy Dana D., Crohns Disease (IBD) Symptoms: Abdominal pain, diarrhea, blood in stool Treatments: Surgeries (colon resection, total proctocolectomy with end ileostomy, abdominal perineal resection, myocutaneous flap), steroids, biologic therapy
Safety outcomes encompassed treatment-emergent and serious adverse events, the presence of anti-cagrilintide antibodies, and changes in blood pressure, pulse rate, high-sensitivity C-reactive protein, plasma renin activity, and aldosterone levels
