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The full-flavor variants are built on a classic American blend recipe: flue-cured Virginia for sweetness, air-cured Burley for body, and Oriental tobacco for aroma, finished with a proprietary casing that contributes the signature taste

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Reactive oxygen species (ROS) formation and dysfunctional endothelial NO synthase (eNOS) contribute to smoking-induced atherosclerosis

In certain Amsterdam neighborhoods, coffeeshop licenses aren't being renewed as readily as they once were, and the number of coffeeshops in the city has fallen from a peak of more than 700 in the mid-1990s to well under 200 today