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In men, significant weight loss from these agents may improve obesity-related hypogonadism, testosterone levels, and cardiovascular risk factors

One thing I will say that is a down fall of the product, is constipation is horrible

Effects depend on what the individual is targeting: Immediate (after 1 session): Feeling refreshed Light hydration boost Subtle glow 46 sessions: Noticeable skin clarity More even tone Improved radiance Long-term (8+ sessions): Deeper antioxidant effects Stable brightening Better skin texture and vitality Sun exposure, hydration, and sleep also influence outcomes

In clinical trials, metformin therapy in PCOS women improves oxidative stress markers, including a decrease in malondialdehyde (MDA) levels and an increase in glutathione (GSH) levels and superoxide dismutase (SOD) enzyme activity (Xu et al., 2022)