& Duek, P
Additionally, NRC-03 and NRC-07, two AMPs from the pleurocidins AMP family, exhibited equal killing effect at a concentration of 50M on normal MCF7 cells and on paclitaxel-resistant breast cancer cell line MCF7-TX400 that possess 2.6 times of P-gp expression more than the normal MCF7 cells, achieving about 60% of cell killing rate
They are not a recommendation, and there is no modern, well-powered, FDA-recognized human trial that establishes a clinically validated dose
Inhibitory interneurons exhibit unique morphology, electrophysiology, and patterns of protein expression, which clearly differentiate them from excitatory cells but, at the same time, are highly heterogeneous among themselves
TB-500 often given systemically)