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MP experiments were set up using SEC-purified shelterin at a final concentration of 1.25 M and incubated with increasing concentrations of compound 40 , in the range 100, 150, 200, 250 and 300 M, and incubated for 1 h at room temperature

Occasional vomiting , typically associated with rapid dose escalation

Die molekulare Integritt und hohe biologische Aktivitt des Peptids bleiben bei normalen Umgebungstemperaturen whrend des gesamten globalen Transports vollstndig erhalten

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CAE provides proof-of-principle that an endogenous disruption of myelin can trigger MS-like brain lesions in an immune-predisposed host