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Concurrent metformin use is well represented in diabetes trials, which often added tirzepatide on top of metformin

M-type potassium channels modulate Schaffer collateral-CA1 glutamatergic synaptic transmission

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Tendons and ligaments: Have low vascularity (limited blood flow) Depend heavily on collagen alignment and remodeling Heal slowly and often incompletely Are prone to scar tissue and reinjury Traditional treatmentsrest, physiotherapy, NSAIDs, corticosteroid injectionscan reduce pain but often do not improve tissue quality