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Given an inferior performance of individual biomarkers in diagnosing early PD, combination of multiple biomarkers may greatly improve the diagnostic efficacy

Fibrogenesis Tissue Repair

Ataxin-3, the MJD1 gene product, interacts with the two human homologs of yeast DNA repair protein RAD23, HHR23A and HHR23B

The independent samples t -test was used for between-group comparisons of normally distributed continuous variables, the MannWhitney U test for non-normally distributed continuous variables, and the chi-square test for categorical variables

However, the molecular determinants underlying this functional dichotomy remain poorly understood, and the systematic frameworks capable of predicting whether Kla will promote or suppress ferroptosis within specific cellular contexts are still lacking