Data depict the mean SD
(1) As a direct adrenergic agonist, ephedrine stimulates post-synaptic - and -adrenergic receptors, increasing peripheral vascular resistance and cardiac contractility
More precisely, among them, the cyclin-dependent kinase inhibitor p21 Cip1/WAF1 , induced by p53 in response to OS and involved in the regulation of cell cycle arrest, replication, cellular proliferation, and apoptosis, competes with KEAP1 for the binding to NRF2 through the DLG motif, thus preventing NRF2 ubiquitination, and increasing its stabilization [184, 185]
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(Definition & Meaning) GHK-Cu is a copper-binding tripeptide a small chain of three amino acids joined to a copper ion studied in laboratory research for its role in tissue signaling, collagen-related pathways, and cellular research models
