It has been proposed that the circulating peptide could access the brain via the ARC and exert its anorectic actions through indirect activation of pro-opiomelanocortin (POMC) neurons in the hypothalamus and through the blocking of fasting ghrelin levels
In fact, dysregulation of the NLRP3 inflammasome is related to the pathogenesis of numerous inflammatory disorders, such as diabetic nephropathy (DN) [36], tumor necrosis factor receptor-associated periodic syndrome (TRAPS) [37], OA [38], and Alzheimers disease (AD) [39]
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Additionally, by assessing at different ages, myopia is also found to be more common among teenagers and adults with Graves'disease [216]
5 Yao S, Chen X, Li S, Zhou L, Bai Q, Zhao C, Huang S