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643, 2009, pp

Pathophysiological studies have demonstrated that elevated plasma lipid levels facilitate the infiltration and deposition of lipids within the arterial intima, subsequently triggering smooth muscle cell proliferation and foam cell formationthe hallmark cellular events in atherogenesis (Figure 1, show that the complicated pathophysiology of AS involves numerous connected pathways, including oxidative stress, lipid accumulation, inflammatory response, and endothelial injury ( Figure 1 Natural organosulfur compounds (OSCs), a class of bioactive molecules with both hydrophilic and lipophilic properties, are predominantly distributed in plant species belonging to the Cruciferae and Liliaceae families ( Freeze-dried preparations of wild garlic (Allium ursinum) cloves have been shown to contain a diverse array of OSCs, with alliin being the predominant form stored in the cytoplasmic compartment of intact cells

Thiagarajan P, Parker CJ, Prchal JT