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It is significant in assisting the organism to safeguard cells against oxidative stress, to detoxify the organism, and to keep the immune system healthy

These recent developments, combined with our observation that complex II inhibition via the succinate dehydrogenase is a druggable and highly potent target for broad-spectrum antiviral inhibition, raise the possibility for the rapid establishment of novel broadly acting antiviral drugs

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For instance, manganese (Mn) supports bacterial oxidative stress resistance through Mn-dependent antioxidant systems 33,34 , and modulates host innate immune signaling pathways to enhance antiviral and antitumor effects 35,36

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