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Data analysis Unless stated otherwise, behavioral data and co-immunoprecipitation data were analyzed by two-way ANOVA with/without repeated measures using IBM SPSS Statistics 21 (IBM Corporation)

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Conversely, inhibitors of PD-1/PD-L1 can selectively attach to either PD-1 or PD-L1, thereby interfering with the PD-1/PD-L1 interaction

All protocols discussed require physician oversight and informed consent