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Brain Behav 11:e2408 Perin MT et al (2023) Homocysteine levels, genetic background, and cognitive impairment in Parkinsons disease

The result is disproportionate loss of lean body mass with relative preservation of fat (or simultaneous fat loss in refractory cachexia)

NAD+ is involved in: Energy production within cells Mitochondrial function Cellular repair and stability Metabolic signaling pathways Because of its central role in how the body functions, researchers are increasingly focused on how supporting this pathway may influence metabolism and body composition

or if you are receiving any medication or treatment that affects bone marrow