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For example, in amyotrophic lateral sclerosis (ALS), HSP70s may modulate mutant proteins such as SOD1, FUS, C9orf72, and TARDBP by preventing their solidification or facilitating their disaggregation and/or clearance via autophagy

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While some individuals report improvements in symptoms, research is still developing, and peptides should generally be viewed as part of a broader arthritis management strategy