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Some evidence also suggests potential benefits for metabolic dysfunction-associated steatotic liver disease (MASLD, formerly known as NAFLD), a common comorbidity in obesity
Structurally, its ortho-dihydroxy (catechol) configuration confers a strong electron-donating capacity, enabling neutralization of ROS via hydrogen-atom transfer and single-electron transfer mechanisms, while its planar conjugated system stabilizes radical intermediates ( 2+ and Cu 2+ , thereby reducing Fenton-type ROS production (Thiruvengadam et al., 2021)
"Small molecule nicotinamide N-methyltransferase inhibitor activates senescent muscle stem cells and improves regenerative capacity of aged skeletal muscle." Biochemical Pharmacology
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