Besides being a potential source of more reactive free radicals via Fenton reaction, physiological generation of H 2 O 2 fulfills a second messenger role and can be transported across membranes by aquaporins, a family of proteins that act as peroxiporins (Sies, 2014)

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acetylcysteine acetylcysteine contraindications, drug interactions, side effects contraindications There are no absolute contraindications for using acetylcysteine in acetaminophen intoxication
It is recommended to test the product on a small area of skin before first use to ensure there is no allergy
36 , e149 (2008)