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A lack of glucokinase prevents glucose from being phosphorylated resulting in lack of glycolysis

Norisoboldine, an alkaloid compound isolated from radix linderae, inhibits synovial angiogenesis in adjuvant-induced arthritis rats by moderating Notch1 pathway-related endothelial tip cell phenotype

The same visual staining intensities were seen in the hippocampus (not shown)

Secondary analysis using an ELISA based approach confirms GPx3 is substantially reduced in children affected with konzo To validate the findings obtained using proteomic-based applications, we sought to determine if the reduced abundance of GPx3 protein in konzo affected children as compared to their unaffected siblings could also be detected using an orthogonal ELISA-based approach