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A very rare, inherited disorder, cTTP is caused by a disease-causing mutation in the ADAMTS13 gene, which is responsible for making the ADAMTS13 enzyme that regulates blood clotting

Chango A, Abdel Nour AM, Niquet C, Tessier FJ

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Those who eat less meat, have autoimmune or thyroid conditions are also more likely to experience anemia caused by vitamin B12 deficiency

However, it does have some limitations, such as the need for special equipment and the inability to distinguish between active and past infections