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NONSTEROIDAL ANTI-INFLAMMATORY DRUGS-INDUCED FAILURE OF LOWER ESOPHAGEAL AND PYLORIC SPHINCTER AND COUNTERACTION OF SPHINCTERS FAILURE WITH STABLE GASTRIC PENTADECAPEPTIDE BPC 157 IN RATS INTRODUCTION We focused on NSAIDs-induced failure of lower esophageal and pyloric sphincter and counteraction of sphincter failure with stable gastric pentadecapeptide BPC 157 (1-7)

The test subjects were housed in a standard animal room under a 12 hour light/12 hour dark day/night cycle with ad libitum access to food and water

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