Changes are typically gradual and compound over time
Specifically, a dose of 200 mg/kg SAE demonstrated the most significant benefits, characterized by a marked reduction in reactive oxygen species (ROS) production, an enhancement of antioxidant defenses within the lens, a decrease in lipid peroxidation, a suppression of apoptotic processes, and an increase in cell proliferation
What it does to you, through a cream or anything else, is a question the dish was never built to answer
doi: 10.1042/bj2270833 Kuchel, PW, Chapman, BE, Endre, ZH, King, GF, Thorburn, DR and York, MJ (1984)
RSI is strictly 1 for a feature whose range never changes over time and strictly 0 for an element whose range oscillates between the extremes