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This review considers the similarity between melanocytes and neurons to provide a valuable model for studies of diseases that involve the nervous system and of innovative therapies

Considering that DDIT4 is involved in the insulin pathway [25] and dexamethasone can induce DDIT4 expression [26], the culture medium of AML12 was removed with insulin and dexamethasone 16 h before the cell treatment [27]

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This is mainly the result of biliverdin and bilirubin formation (24)