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The relevance here is evidential, not procedural: because delivery and stability vary so much, comparing results across products and studies is genuinely difficult, and that heterogeneity is one reason a clean answer to the title question has been so slow to emerge

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Table 1 Therapeutic strategies targeting hypoxia and metabolic reprogramming in cancer

Thats why when a scientist discovers a particular protein thats important in a cellular process or disease, one of the first things they will do is examine its molecular interactions