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Description

Gut Microbes 15:2244720

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1995 Dec;29(12):1263-73. [PMID: 8672832]

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In the early stages of AD, the number of autophagosomes increases, but these autophagosomes do not fuse normally with lysosomes, and toxic proteins, including amyloid (A), tau protein, and damaged mitochondria, cannot be cleared before they cause damage [181,182,183]

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Along with the formation of GSNO after reaction with GSH, NO can readily react with the sulfhydryl group (-SH) of protein cysteine residue to form S-nitrosocysteine that consists of a redox-mediated posttranslational modification

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Previously, it was shown that pentadecapeptide BPC 157-dopamine system interaction is quite complex

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