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Alpha-Arbutin complements this pathway by refining uneven pigmentation while preserving barrier integrity and skin balance

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Hepatic growth hormone receptors respond to circulating HGH, triggering intracellular signalling cascades that upregulate IGF-1 transcription and synthesis

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Involvement of oxidative stress in PD is further substantiated through ROS induced Parkinsonian models and elevated oxidative markers in clinical PD samples