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Foxo4dri is a senolytic peptide that disrupts the p53 gene, causing apoptosis in ageing cells

For a side-by-side of how this compares to the dual and single agonists, see our breakdown of Retatrutide vs Semaglutide vs Tirzepatide

In addition, the pro-oxidant/antioxidant effects of polyphenols and vitamins are context-dependent and moderate doses may be cardioprotective while supraphysiologic levels negatively affect the oxidative state or disrupt ROS-mediated signalling that is important for chemotherapy-induced killing of tumour cells (218)

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