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Throughout the 0-32 week treatment period, adverse outcomes and the occurrence of anti-cagrillintide antibodies were assessed in addition to any changes in systolic and diastolic blood pressure, pulse rate, plasma high-sensitivity C-reactive protein, aldosterone, and the activity of renin

In the controls, there were no significant changes compared to the 1st week

Additionally, the lower concentration of benzyl alcohol found in bacteriostatic water for peptide reconstitution prevents it from affecting the stability or integrity of the peptide being dissolved in it

In some embodiments, the otic formulation or composition comprises about 0.1% by weight of the cholesterol

It is a synthetic tetrapeptide, composed of four amino acids: alanine, glutamic acid, aspartic acid, and glycine