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Their data indicated the importance of targeting the tumor microenvironment by blocking epigenetic mechanisms, which control critical events for colonization such as HGF/c-Met axis as a potential therapy of bone metastasis [40]

In the present article, the synthetic process of melanogenesis and associated core signaling pathways are summarized

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Possible production of free radicals through an erythrocyte-mediated positive feedback mechanism

Based on these results, we speculate that by regulating and orchestrating the expression of these ECM genes, MB may reduce the formation of skin wrinkles