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Clinical manifestations of NMS include hyperpyrexia, muscle rigidity, altered mental status, and evidence of autonomic instability (irregular pulse or blood pressure, tachycardia, diaphoresis, and cardiac dysrhythmia)

Institutional focus

Expected timeline based on research: Initial vascular effects may begin within the first week

It has numerous important roles in the body, such as improving resistance to stress, aiding digestion, promoting healthy skin, reducing muscle spasms, regulating blood pressure, and supporting energy production, detoxification, nerve transmission, blood formation, protein and fat synthesis, steroid hormone production, and blood sugar maintenance

Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3)