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To counteract this oxidative damage induced by paraquat, and MPTP, astrocytes seem to protect dopaminergic neurons by increasing expression of antioxidant molecules, such as heme oxigenase1 (EC 1.14.99.3), glutathione S-transferase P (EC 2.5.1.18) and glutathione [90,91]

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Glutathione is a tripeptide consisting of glutamicglycinecysteine and is found in reduced (GSH) and oxidized (GSSG) forms (Figure 1)

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