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Felsenstein, J

If you feel great and your energy levels are steady, youve likely found your "sweet spot." If you begin to feel bloated or "off," simply scale back

Genetic variants of methyl metabolizing enzymes and epigenetic regulators: associations with promoter CpG island hypermethylation in colorectal cancer

Used in explaining increased frequency of seizures in epilepsy and progression of bipolar disorder in humans. Jason et al have recently (2011) proposed kindling as an etiological model for ME/CFS : Kindling might represent a heuristic model for understanding the etiology of Myalgic Encephalomyelitis/chronic fatigue syndrome (ME/CFS)

Emerging research includes Nutrigenomic mapping, Gut microbiota, Combination therapies, AI/ML in dietary planning, long term RCTs