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The addition of 75 g/kg methyl-cobalamin injected twice weekly for one month further normalised GSH:GSSG

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114 Gastrodin (GAS), derived from Gastrodia elata , along with Irisin, a soluble peptide upregulated by the PGC-1 signaling pathway, and Mitochonic acid-5, a mitochondrial homing drug, all activate the SIRT3/Parkin pathway, thus enhancing mitochondrial membrane potential and promoting mitophagy