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Understanding the difference between native tobaccos used in traditional ceremonies and the commercially manufactured product could help tribal members quit smoking.

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(XLSX) Acknowledgments The authors would like to thank the following for providing nicotine and e-liquid samples and helpful discussions: Anthony Dillion (Twelfth State Brands), Tricia Desmarais (My Vape Order, Inc.), Rob Reisel (Turning Point Brands), Kevin Burd (North America Nicotine), George Cassels-Smith (eLiquiTech), and Tony Nash (VapinDirect)