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Despite growing popularity, minimal human data exists

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Last reviewed: May 14, 2026 Last updated: May 14, 2026 Written by: Jay Hastings, CEO of PlexusDx Jay Hastings is the CEO of PlexusDx, a precision health company focused on genetic testing, blood biomarker insights, and personalized wellness recommendations

While these injections are becoming popular for those looking to enhance their health, there are questions surrounding their effectiveness

The appearance of a pustular/papular rash associated with high levels of Vitamin B12 is well described in the medical literature even though the exact mechanism appears to be unknown