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Synthetic lethal screening identifies compounds activating iron-dependent, nonapoptotic cell death in oncogenic-ras-harboring cancer cells

Acknowledgements The authors acknowledge the help of Dr

It is both a mutagen due to its ability to initiate and promote cancer development, as well as a nonspecific damaging factor 5

The nonenzymatic initial reaction between 1 M roGFP2 WT (S 2 ) and physiological millimolar GSH concentrations was too slow to be detectable and to be of any relevance in the presence of glutaredoxins in accordance with previous analyses 32

56 This dynamic balance ensures that neutrophils function as an immune defense without causing additional damage to the organism