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Severe vitamin E deficiency results mainly in neurological symptoms, including impaired balance and coordination (ataxia), injury to the sensory nerves (peripheral neuropathy), muscle weakness (myopathy), and damage to the retina of the eye (pigmented retinopathy)

21 However, whether the production is directly linked to 1-antitrypsin deficiency per se or results from altered autophagy induced by the mutant 1-antitrypsin Z requires further study

In addition, White et al

Cell Counting Kit-8 (CCK-8) cytotoxicity assays on (A) HEK293T cells, (B) HGC-27 cells and (C) HeLa cells

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